How Much Nicotine is in a Vape? Compared to Cigarette How Many Packs of Cigarettes are in a Vape? How Many Puffs of Vape Equal a Cigarette? Say no to vaping. 10 15 vape puffs are roughly equivalent to one cigarette. We want to encourage and support families to have open and engaging conversations with young people to Vape vs Cigarette Nicotine: How Many 5% Vape Puffs Equal One Cig? Comparison of Nicotine Levels Between Cigarettes and Vapes Ecigator