Pigmented skin lesions The BMJ Pigmented Lesions and Melanoma Plastic Surgery KeyPlastic Surgery Key COM Dec. 2011 Diagnosis UW School of Dentistry Oral Melanotic Macule: Symptoms and Treatment Skinsight Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier Hunziker syndrome