Oral Melanotic Macule MEDizzy Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360 Labial Macules: Dark Spots on the Lip Dermatology Advisor Labial Melanotic Macules in Atopic Dermatitis: An Observational Study Semantic Scholar Pathology Outlines Melanotic macule This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips.