Pigmented Lesions of the Oral Cavity Oral and Maxillofacial Surgery Clinics Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Clinical features of oral pigmented lesions: ( ) Nevus, ( ) melanotic Download Scientific Diagram This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding Nevi and Malignant Melanoma Plastic Surgery KeyPlastic Surgery Key Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule.